Pseudomonas aeruginosa Phenotypes Associated With Eradication Failure in Children With Cystic Fibrosis
نویسندگان
چکیده
منابع مشابه
Pseudomonas aeruginosa phenotypes associated with eradication failure in children with cystic fibrosis.
BACKGROUND Pseudomonas aeruginosa is a key respiratory pathogen in people with cystic fibrosis (CF). Due to its association with lung disease progression, initial detection of P. aeruginosa in CF respiratory cultures usually results in antibiotic treatment with the goal of eradication. Pseudomonas aeruginosa exhibits many different phenotypes in vitro that could serve as useful prognostic marke...
متن کاملEradication of Pseudomonas aeruginosa in cystic fibrosis.
We read with interest the recently published article by TACCETTI et al. [1] in the European Respiratory Journal and the accompanying editorial by JONES [2]. TACETTI et al. [1] report on their experience with early eradication therapy against Pseudomonas aeruginosa (PA) in cystic fibrosis (CF), concluding that this treatment exerts a number of beneficial effects and is also cost-effective. Howev...
متن کاملEradication of Pseudomonas aeruginosa in adults with cystic fibrosis
BACKGROUND Eradication of new infection of Pseudomonas aeruginosa is an important intervention in managing cystic fibrosis (CF). Previous trials, studying predominantly under 18-year-olds, indicate that antibiotic eradication therapy (AET) has success rates of 62.8-93.0%. In this retrospective cohort study, we report the outcomes of AET in an adult population. METHODS Adults with a confirmed ...
متن کاملAcquisition of Pseudomonas aeruginosa in children with cystic fibrosis.
OBJECTIVE This study was pursued as an extension of a randomized clinical investigation of neonatal screening for cystic fibrosis (CF). The project included assessment of respiratory secretion cultures for pathogens associated with CF. The objective was to determine whether patients diagnosed through neonatal screening and treated in early infancy were more likely to become colonized with Pseud...
متن کاملEradication Therapy against Pseudomonas aeruginosa in Non-Cystic Fibrosis Bronchiectasis.
BACKGROUND No prospective study has assessed eradication treatment of early Pseudomonas aeruginosa colonisation in bronchiectasis not due to cystic fibrosis (CF). OBJECTIVES To evaluate the efficacy of 3 months of nebulised tobramycin after a short course of intravenous antibiotics in the eradication of P. aeruginosa and its clinical consequences in non- CF bronchiectasis following initial P....
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2014
ISSN: 1058-4838,1537-6591
DOI: 10.1093/cid/ciu385